The Thermo Scientific LTQ Orbitrap Velos combines the proven mass accuracy and ultra-high resolution of the Orbitrap mass analyzer, with the increased sensitivity and improved cycle time of the LTQ Velos™. The high mass accuracy of the LTQ Orbitrap Velos increases the speed and confidence of identification in complex samples by minimizing false positive identification. The ultra-high resolution provides certainty in analytical results by enabling molecular weight determination for intact proteins and in-depth analysis of isobaric species. The new HCD cell in the LTQ Orbitrap Velos is more efficient, resulting in improved quantitation of isobaricallylabeled peptides, such as applications requiring Tandem Mass Tags (TMT). Electron Transfer Dissociation (ETD) generates complementary information for highly sensitive PTM analyses and de novo sequencing.